Wnt is a large family of secreted proteins, among which there is a classic Wnt signaling pathway. Wnt3A is the major ligand of the Wnt signaling pathway. During embryonic development, Wnt3A is essential for the normal development, anterior and posterior patterns, somatic development, and tail bud formation of the hippocampus. Wnt3A can also promote the self-renewal of hematopoietic stem cells, neural stem cells, and embryonic stem cells.
Test items and data
Bacteria, Fungi
Mycoplasma
Lactate dehydrogenase-enhanced virus (LDEV)
Endotoxin
Negative
Negative
PCR negative
<4 EU/mL
Product Advantages
• Promotes cell growth and proliferation: WRN growth factor can stimulate cell division and proliferation, helping to maintain the normal growth state of cells.
• Promotes DNA repair: WRN proteins play an important role in the DNA repair process, helping cells repair damaged DNA and reduce the occurrence of genetic mutations.
• Anti-aging effect: The WRN gene is closely related to the cellular aging process. WRN growth factor can slow down the cellular aging process and maintain the youthful state of cells.
Application directions
• Cell biology research: Applicable to important research areas such as DNA damage repair mechanisms, cell cycle regulation, and cell proliferation and apoptosis.
• Medical research: Because mutations in the WRN gene can lead to a rare genetic disease—Werner syndrome, which is characterized by premature aging and senescence, WRN growth factor can be used to study the pathogenesis, treatment, and other cellular senescence and aging-related diseases of Werner syndrome.